Aims and objectives

The ESCMID Study Group for Clostridioides difficile (ESGCD) is committed to spreading awareness on C. difficile infections by fostering collaboration across European centres and providing a forum for knowledge sharing. Together, this group is dedicated to:

  • Ensuring patient perspectives are central to C. difficile discussions
  • Overseeing the development of European guidelines on the prevention, diagnosis, treatment, and surveillance of C. difficile infections
  • Developing extensive educational webinars on C. difficile infection, including insights from early career researchers and trainees in clinical microbiology and infectious diseases (CM/ID)
  • Supporting research collaborations, educational meetings, and publications related to C. difficile

Activities and resources

ESGCD Newsletter, December 2024

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ESGCD Newsletter, September 2024

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Antimicrobial susceptibility in Clostridioides difficile varies according to European region and isolate source

Freeman J, Viprey V, Ewin D, Spittal W, Clark E, Vernon J, Fawley W, Davis G, Tkalec V, Wilcox M, Rupnik M, Davies K; COMBACTE-CDI Consortium. JAC Antimicrob Resist. 2024 Jul 23;6(4):dlae112

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Heterogeneity in practices to reduce the risk of transmission of Clostridioides difficile in healthcare settings: a survey of ESCMID Study Group for Clostridioides difficile (ESGCD) members

Khanafer NL, Fitzpatrick F, Barbut F, Krutova M, Davies K, Guery B, Vanhems P. Eur J Clin Microbiol Infect Dis. 2024 Apr;43(4):785-7894

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The ESCMID Study Group for Clostridioides difficile: History, Role, and Perspectives

Coia JE, Kuijper EJ, Fitzpatrick F. Adv Exp Med Biol. 2024;1435:351-362

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Distribution of Clostridioides difficile ribotypes and sequence types across humans, animals and food in 13 European countries

Rupnik M, Viprey V, Janezic S, Tkalec V, Davis G, Sente B, Devos N, Muller BH, Santiago-Allexant E, Cleuziat P, Wilcox M, Davies K; COMBACTE-CDI consortium. Emerg Microbes Infect. 2024 Dec;13(1):2427804

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Hear my voice: involving patients in Clostridioides difficile infection research. 

Strawbridge J, Heritage J, Krůtová M, Guery B, Davies K, Fitzpatrick F, Freeman J. Clin Microbiol Infect. 2023;29(10):1222-1224.

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In vivo emergence of a still uncommon resistance to fidaxomicin in the urgent antimicrobial resistance threat Clostridioides difficile

Marchandin H, Anjou C, Poulen G, Freeman J, Wilcox M, Jean-Pierre H, Barbut F. J Antimicrob Chemother. 2023;78(8):1992–1999.

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European survey on the current surveillance practices, management guidelines, treatment pathways and heterogeneity of testing of Clostridioides difficile, 2018- 2019: results from The Combatting Bacterial Resistance in Europe CDI (COMBACTE- CDI).

Viprey VF, Granata G, Vendrik KEW, Davis GL, Petrosillo N, Kuijper EJ, Vilken T, Lammens C, Schotsman JJ, Benson AD, Cataldo MA, van der Kooi TII, Wilcox MH, Davies KA; COMBACTE-CDI consortium. J Hosp Infect. 2023;131:213–220

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Faecal microbiota transplantation for first and second episodes of Clostridioides difficile infection. 

Van Prehn J, Fitzpatrick F, Kuijper EJ; European Study Group for Clostridioides difficile and the European Study Group for Host and Microbiota Interaction. Lancet Gastroenterol Hepatol. 2023;8(2):109.

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Faecal microbiota transplantation for first and second episodes of Clostridioides difficile infection. 

Krutova M, Davies K, Guery B, Barbut F. Lancet Gastroenterol Hepatol. 2023;8(2):111-112.

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The effect of antibiotic therapy for Clostridioides difficile infection on mortality and other patient-relevant outcomes. 

Van Prehn J, Skinner AM, Krutova M, Guery B. Clin Microbiol Infect. 2024;30(2):261–262.

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Hear my voice: involving patients in Clostridioides difficile infection research. 

Strawbridge J, Heritage J, Krůtová M, Guery B, Davies K, Fitzpatrick F, Freeman J. Clin Microbiol Infect. 2023;29(10):1222-1224.

Go to publication


In vivo emergence of a still uncommon resistance to fidaxomicin in the urgent antimicrobial resistance threat Clostridioides difficile

Marchandin H, Anjou C, Poulen G, Freeman J, Wilcox M, Jean-Pierre H, Barbut F. J Antimicrob Chemother. 2023;78(8):1992–1999.

Go to publication


Which trial do we need? A sequential multiple assignment randomized trial to determine the optimal Clostridioides difficile treatment sequence. 

Van Prehn J, van Werkhoven CH, Skinner AM, Guery B, Dubberke ER, Kuijper EJ. Clin Microbiol Infect. 2024;30(2):165–169.

Go to publication


European survey on the current surveillance practices, management guidelines, treatment pathways and heterogeneity of testing of Clostridioides difficile, 2018- 2019: results from The Combatting Bacterial Resistance in Europe CDI (COMBACTE- CDI).

Viprey VF, Granata G, Vendrik KEW, Davis GL, Petrosillo N, Kuijper EJ, Vilken T, Lammens C, Schotsman JJ, Benson AD, Cataldo MA, van der Kooi TII, Wilcox MH, Davies KA; COMBACTE-CDI consortium. J Hosp Infect. 2023;131:213–220

Go to publication


Faecal microbiota transplantation for first and second episodes of Clostridioides difficile infection. 

Van Prehn J, Fitzpatrick F, Kuijper EJ; European Study Group for Clostridioides difficile and the European Study Group for Host and Microbiota Interaction. Lancet Gastroenterol Hepatol. 2023;8(2):109.

Go to publication


Faecal microbiota transplantation for first and second episodes of Clostridioides difficile infection. 

Krutova M, Davies K, Guery B, Barbut F. Lancet Gastroenterol Hepatol. 2023;8(2):111-112.

Go to publication

How to – differences in policies for FMT

21 January 2025, 15:00-16:00 CET

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ESGCD: The Xmas webinar: 3 “cases” selected from ECR abstract submissions

9 December 2024, 15:00 CET

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An update on molecular typing of C. difficile

10 September 2024, 15:00 CET

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Back to Basics: Surveillance and IPC

9 February 2024

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ESGCD Xmas case series webinar 

December 6

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ESGCD Back to basics: Treatment of CDI 

July 6

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Update on Live biotherapeutic products and FMT-like treatments for recurrent Clostridioides difficile infections (ESGCD and ESGHAMI)

June 21

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ESGCD Back to basics: Listening and responding to patients experiencing C. difficile infection 

June 6

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ESGCD Back to basics: Diagnosis of C. difficile Infection 

March 22

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IV International Latin American Clostridioides difficile symposium 

Congress/Conference

Go to course


Anaerobe meeting

Congress/Conference

Go to course


8th Clostridioides difficile day

Technical workshop


ESCMID postgraduate course on clinical studies 

Post-graduate course


Better methods for clinical studies in Infectious Diseases and Clinical Microbiology

Post-graduate course

Go to course

Executive Committee

  Kerrie Davies

Kerrie Davies

Chair
University of Leeds and Leeds Teaching Hospitals NHS Trust. Microbiology.
Leeds, United Kingdom
  John E. Coia

John E. Coia

Treasurer
University of South Denmark
Esbjerg, Denmark
  Benoit Guery

Benoit Guery

Science Officer
CHUV. Infectious Diseases.
Lausanne, Switzerland
  Wiep Klaas Smits

Wiep Klaas Smits

Education Officer
Leiden University Medical Center
Leiden, Netherlands
  Erik Dubberke

Erik Dubberke

Secretary
Washington University
St.Louis, United States
  John Heritage

John Heritage

Ad hoc: Patient Representative
University of Leeds. Faculty of Biological Sciences.
York, United Kingdom
  Andrea Marino

Andrea Marino

Ad hoc: TAE Representative
University of Catania. Clinical and Experimental Medicine.
Catania, Italy

Contact

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