Epi Alert

Summary: 30 June 2026

A rapidly expanding Bundibugyo Ebola virus outbreak in eastern DRC and Uganda has caused over 1,000 cases and 254 deaths, complicated by a lack of approved vaccines and community resistance. Mpox transmission remains active globally, with Madagascar reporting 2,161 confirmed clade Ib cases and eight deaths since December 2025, while European surveillance notes 608 clade I and 854 clade II cases over the past year. A multi-country Salmonella bovismorbificans ST377 outbreak linked to alfalfa sprouts has resulted in 109 cases and two deaths across Europe. Yellow fever activity continues, with 79 human infections in the Americas and 16 confirmed cases in Africa. In Spain, a seasonal Crimean-Congo hemorrhagic fever case was reported in Castilla y León. Elsewhere, Bangladesh recorded 97,522 suspected measles cases and 702 deaths. WHO provides an update of the previously reported Nipah virus case in Kerala.

Highlights

Yellow fever - Global
From 1 January to 26 May 2026, six countries in the Americas reported 79 human infections alongside multiple epizootics, indicating active sylvatic circulation. In Africa, sustained activity continued across 13 high-risk countries classified under the Eliminate Yellow Fever Epidemics (EYE) Strategy; from January to May 2026, three African countries reported 16 confirmed cases, with 32 suspected cases under investigation in five others

Crimean-Congo hemorrhagic fever - Spain
A seasonal case of Crimean-Congo hemorrhagic fever was reported in June 2026 in Salamanca, Castilla y León, amid sustained enzootic virus circulation. The region previously recorded two confirmed cases in 2025, indicating the continued presence of the virus in western Spain.

Salmonellosis - Europe
A multi-country foodborne outbreak of Salmonella Bovismorbificans ST377 linked to alfalfa sprouted seeds has resulted in 109 cases and two deaths across Europe. Finland has reported 32 laboratory-confirmed cases, with infections also identified in at least six other European countries. The outbreak is suspected to be linked to the consumption of raw sprouts.

Ebola virus disease - Africa
A rapidly expanding outbreak of Bundibugyo Ebola virus disease is affecting eastern DRC and Uganda. As of 22 June 2026, DRC has reported over 1000 cases and 254 deaths, while Uganda reported one new case. Containment is severely challenged by the lack of approved vaccines or treatments, degraded water/sanitation/hygiene infrastructure, community resistance to testing, and infections among healthcare workers.

Mpox - Global
Mpox surveillance in late June 2026 spans European and global pictures. In Europe, over the past 12 months, 18 countries reported 608 clade I cases and 19 reported 854 clade II, 92% of both clades occurred among men who have sex with men; hospitalization was 14% (clade I) and 8% (clade II), with one clade II death. Globally, both clades circulate via sexual contact. African clade II outbreaks (Ghana, Guinea, Liberia) affect young adults; outside Africa, cases are predominantly adult males who have sex with men. Travel-associated cases continue appearing worldwide. Madagascar's clade Ib outbreak, ongoing since mid-December 2025, recorded 3,505 suspected and 2,161 confirmed cases by 17 June, with eight deaths, both detailed fatalities immunocompromised. Toamasina is the epicenter, with spread across five urban centers indicating entrenched transmission and likely under-detection.